Hi,
your WPHP app is being extremely helpful in my effort in integrating RoundCube (php based) into twisted.web2!

I had to patch line 370 in file fcgi_app.py:

header, value = line.split(':',1)

Otherwise headers with multiple : produce exceptions. For example:
"Expires: Thu, 01 Dec 1994 16:00:00 GMT"

Kind regards,
DQ